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ea0037ep596 | Obesity and cardiovascular endocrinology | ECE2015

Increased expression of ATP-binding cassette transporter A1 by cilostazol may be a possible mechanism for its protective effect against hepatic steatosis

Cha Bong-Soo , Park Tae Sun , Jeon Byung Hun , Lee Yong-Ho , Yun Mi Ra , Lee Byung Wan , Kang Eun Seok , Lee Hyun Chul

Objective: Cilostazol, a selective inhibitor of phosphodiesterase 3, which has been widely used in patients with atherosclerotic diseases, is known to have additional beneficial effects on dyslipidemia. ATP-binding cassette transporter A1 (ABCA1) plays a critical role in the regulation of intracellular cholesterol levels in hepatocytes. We aimed to investigate the effect of Cilostazol on hepatic steatosis and its underlying mechanism related to ABCA1.Met...

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Endocrine Abstracts

Increased expression of ATP-binding cassette transporter A1 by cilostazol may be a possible mechanism for its protective effect against hepatic steatosis

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